On the other hand, the repressive effect of miR21 on RECK expression has been described in cancerous tissues or cells, e.g., glioma [51,52], oral cancer [53], gastric cancer [54], prostate cancer [55], and hepatocellular carcinoma [56,57], as well as non-transformed tissues and cells, like mesenchymal stem cells [58], cardiac fibroblasts [59], and renal tubules [60]. This evidence concerns the gene RECK and Familial prostate cancer.