HAO1 CN gain also predicted poor overall survival for tumours that were ER+, ER+/PR+, and ER+/PR− (Figure 5B,D,E; p = 0.002, p = 0.040 and p = 0.018, respectively) but not in ER negative tumours (Figure 5C; p = 0.998). This evidence concerns the gene HAO1 and neoplasm.