COL1A1 and leiomyoma: As shown in Figure 5C,D, the anti-miR-135b transfection following LINCMD1 knockdown partially reversed the protein levels of APC, non-phosphorylated β-Catenin at Ser45, total β-Catenin, and COL1A1, supporting the existence of a LINCMD1/miR-135/APC/β-Catenin signaling axis in leiomyomas which contributes to ECM accumulation in leiomyomas.