SERPINE1 and coronary artery disorder: To answer these questions, we designed a genetic epidemiological study to test for associations between CAD risk in the Korean population and five polymorphisms of miRNAs binding to the 3′-UTR of the PAI-1 gene: miR-30c rs928508 A > G, miR-143 rs41291957 G > A, miR-143 rs4705342 T > C, miR-145 rs353291 T > C, and miR-181a2 rs10760371 T > G.