From an in silico analysis, we found that a high expression of MAP1LC3B (along with that of BECN1 and with low expression of p62/SQSTM1) and the high expression of BNIP3 (along with that of PRKN and of MAP1LC3B), which together are indicative of increased autophagy and mitophagy, correlate with a better prognosis in AML patients. This evidence concerns the gene PRKN and acute myeloid leukemia.