All the stratification signatures with low glycolysis and high autophagy–mitophagy correlated with a better clinical outcome for AML patients, and the most significant difference was observed with PFKM/MAP1LC3B (p = 0.0004) and PFKM/BNIP3 (p = 0.0030) signatures (Figure 6C,D), followed by PKM/MAP1LC3B and PKM/BNIP3 (Figure 6E,F) and HK2/MAP1LC3B and HK2/BNIP3 (Figure 6A,B), reflecting the trend in individual prognostic analysis described above. The gene discussed is HK2; the disease is acute myeloid leukemia.