LDHA and neoplasm: Finally, we should not neglect the role of ALDHs in other cell types present in the tumor microenvironment, such as macrophages (e.g., ALDH1A2 is associated with M2 macrophages and may represent a marker for a subset of such cell types, which have a known protumoral effect [73]), hinting at an additional beneficial effect of ALDH inhibition in GB treatment.