Research has indicated that the deficiency of circadian rhythm-related transcription factors in mice brain and muscle aryl hydrocarbon receptor nuclear translocator-like protein 1 (Bmal1), circadian locomotor output cycles protein kaput (Clock), and period 1 (Per1) resulted in detrimental outcomes including implantation failure, miscarriage, and infertility [20,21]. Here, BMAL1 is linked to spontaneous abortion.