TP53 and neoplasm: Specifically, the TP53 PV (NM_000546.5):c.532del p.(His178Thrfs*69) in exon 5 of 11 exons) was observed with a variant allele frequency (VAF) of 78%, and the CHEK2 PV (NM_007194.4):c.85C>T p.(Gln29*) in exon 2 of 15 exons) was detected with a VAF of 25% in the tumor tissue.