Curcumin—Curcumin has been reported to induce cell cycle arrest and apoptosis in thyroid cancer cells through NF-κB inhibition [84], while the simultaneous use of AZD6244, an MAPK inhibitor, and bortezomib results in a highly effective combinatorial tool to reduce the growth rate, migration, and survival of thyroid cancer cells in vitro and in vivo [85]. The gene discussed is NFKB1; the disease is thyroid gland carcinoma.