PTEN and thyroid gland carcinoma: Four years later, Ludwig and co-workers demonstrated that NF-κB mediated the protumorigenic activity of RET oncogene in parafollicular C cells [41], while the prosurvival role of NF-κB in thyroid carcinoma cells started to be uncovered by different studies describing its ability to overcome TGF-β-, PTEN-, and radiation-induced apoptosis [42,43,44].