Overexpression of SUV39H2 is a common phenomenon in multiple cancer types, including hematopathies (e.g., leukemias and lymphomas), breast cancer, digestive system cancers (e.g., colorectal carcinoma), lung cancer, urinary and reproductive system cancers (e.g., prostate cancer), and Bowen’s disease [108,109,110]. The gene discussed is SUV39H2; the disease is cancer.