Overexpression of SUV39H2 is a common phenomenon in multiple cancer types, including hematopathies (e.g., leukemias and lymphomas), breast cancer, digestive system cancers (e.g., colorectal carcinoma), lung cancer, urinary and reproductive system cancers (e.g., prostate cancer), and Bowen’s disease [108,109,110]. This evidence concerns the gene SUV39H2 and colorectal carcinoma.