Transferrin (Tf)-modified poly(ethylene glycol)-phosphatidylethanolamine (mPEG-PE) micelles loaded with the poorly water-soluble drug R547, a potent and selective ATP-competitive cell-cycle protein-dependent kinase (CDK) inhibitor, exhibited high targeting efficiency and therapeutic efficacy against ovarian cancer in both in vitro and in vivo experiments [32]. Here, TF is linked to ovarian cancer.