BCR and diffuse large B-cell lymphoma: Then, let us mention the work that (i) assumes several subsets of DLBCL with different pathogenetic mechanisms, (ii) employs comprehensive GEP, covering approximately 33,000 genes, (iii) applies different unsupervised clustering methods, e.g., self-organizing maps, and (iv) describes three discrete subsets of DLBCL, which were interpreted based on the affected pathways: the oxidative phosphorylation (OxPhos) cluster, the BCR/proliferation cluster, and the host response (HR) cluster of tumors (Table 2).