The Asian Cancer Research Group (ACRG) [12] established an alternative classification based on data solely from Asian patients, who were categorized into four molecular subtypes: (1) mesenchymal-like type, which includes diffuse-subtype tumors with the worst prognosis; (2) Microsatellite unstable tumors, which are hypermutated intestinal-subtype tumors with the best overall prognosis; and (3) TP53-active and (4) TP53-inactive types, which include patients with intermediate prognosis. Here, TP53 is linked to cancer.