Although we previously reported that MAdCAM-1 and its lymphocyte ligand α4β7 integrin mediate the migration of B cells to pan-LNs of young NOD mice [12], there are no studies that directly examine the role of MAdCAM-1 in the migration of T cells into pan-LNs in the NOD mouse model of T1D [39]. The gene discussed is MADCAM1; the disease is type 1 diabetes mellitus.