An increased ALP was noted in six out of seven dogs, four out of seven dogs had an increased ALT, six out of seven dogs had an increased AST, two out of seven dogs had an increased GGT, four out of seven dogs had an increased CK, two out of seven dogs had hyperalbuminemia, five out of seven dogs had hypercholesterolemia, one dog out of seven had hypocalcemia, one out of the seven dogs had hypercalcemia, one out of the seven dogs had hypertriglyceridemia, and four out of seven dogs had hyperglycemia. The gene discussed is GPT; the disease is familial hypercholesterolemia.