In the study by Silveira et al., the one reported patient who aspirated in the GLP-1 RA group was a 63-year-old man with obesity (BMI 37.7), prior history of gastric bypass, and semaglutide use (last taken 11 days prior), who had adequately fasted (12.4 h for solids and clear fluids) and reported no digestive symptoms prior to his endoscopy and was not specifically reported to have any negative sequelae following his aspiration event [40]. This evidence concerns the gene GLP1R and obesity due to melanocortin 4 receptor deficiency.