The prospective study by Sen et al. reported higher retained gastric contents in the GLP-1 RA group compared to the non-user group (56% versus 19%) evaluated by preprocedural gastric ultrasound; of note, the patients had confounding factors, including diabetes, GERD, home opioid use, and high ASA physical status classification [35]. The gene discussed is GLP1R; the disease is gastroesophageal reflux disease.