The association with spondylarthritis, enthesitis, uveitis, non-bacterial osteomyelitis (NBO), or chronic-recurrent multifocal osteomyelitis (CRMO) has to be considered with 30% positive testing for antinuclear antibodies (ANAs) and 50% for Human Leukocyte Antigen B (HLA) B27. This evidence concerns the gene MRAP and uveitis.