CDKN2B-AS1 and atherosclerosis: Though GWAS studies have consistently found connections between the genomic region containing ANRIL and the risk of developing T2DM and CAD, the genetic factors associated with these conditions at the ANRIL locus tend to be distinct, with atherosclerosis-related SNPs scattered throughout the ANRIL gene and T2DM SNPs located further away from the last exon of ANRIL [12].