TARBP2 and thyroid gland carcinoma: To investigate whether mitosis-dependent downregulation of TRBP2 is specific for thyroid cancer cells, we next examined its (TRBP2) protein expression profiles in the three human urothelial bladder-cancer cell lines (a) RT112 (malignancy grade I/II), (b) T24 (malignancy grade III), and (c) TCCSUP (malignancy grade IV).