A lack of resolution in anemia (Hgb HR 3.10; Hct HR 2.53; p < 0.001), hypercalcemia (HR 3.98, p < 0.001), elevated CRP (HR 2.11, p < 0.001), elevated ESR (HR 3.01, p < 0.001), elevated LFTs (HR 1.92, p = 0.014), and elevated NLR (HR 1.80, p = 0.016) were associated with significantly worse OS. This evidence concerns the gene CRP and Hypercalcemia.