It inhibits ferroptosis in TSCC cells by inhibiting miR-125b-5p and enhancing SLC7A11 [34], while in acute myeloid leukemia (AML), muscle ARNT-Like protein-1 (Bmal1) prevented RSL3-induced ferroptosis through EZH2-mediated EBF3 methylation to inhibit the expression of EBF3 and ALOX15 [56]. This evidence concerns the gene EZH2 and acute myeloid leukemia.