The normalization of MCAM, VE-cadherin, and Endoglin expression by CBD supports the anti-angiogenic and anti-proliferative effect of CBD that has been described in vitro for HUVECs, but also in vivo, such as vascularization models in MatrigelTM sponges [17] and reduction of tumor angiogenesis [55]. The gene discussed is CDH5; the disease is neoplasm.