BTK and myelodysplastic syndrome: In fact, as BTK has been shown to regulate activation of the inflammasome, a multiprotein complex involved in innate immune responses [134], it is also a potential molecular target in inflammasome-driven diseases, such as myelodysplastic syndromes (MDSs) [135] or solid tumors (e.g., breast, lung, prostate, colorectal, etc.)[136].