EGFR and non-small cell lung carcinoma: Systemic treatment with a tyrosine-kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR) has become a standard treatment of care for advanced non-small cell lung cancer (NSCLC) harboring activating mutations in the EGFR gene such as deletions in the exon 19 (del19) and a point mutation in the exon 21 (L858R) [1].