These variables included age, male sex, hypertension, serum albumin levels, eGFR, urine PCR, immunosuppressants use, mesangial hypercellularity, endocapillary hypercellularity, tubular atrophy/interstitial fibrosis, cellular or fibrocellular crescents, and urinary mRNA levels of FLOT1, Nephrin, and TfR. The gene discussed is NPHS1; the disease is hypertensive disorder.