We compared the transcriptome of splenic OT-I (transgenic T cell with TCR specific to ovalbumin (OVA)) effector T cells responding to vacciniaOVA, tumor-draining lymph node (dLNs) naive CD8+ T cells, Tpex cells (CD8+PD1intTim3−Slamf6hiTOXint) and Tex cells (CD8+PD1hiTim3+Slamf6loTOXhi) from murine B16 melanoma tumors (Extended Data Figs. 1 and 2a–d)21. Here, CD8A is linked to melanoma.