In order to investigate whether re-expression of ZBTB18 in GBM cells is able to affect their ability to communicate with the tumor microenvironment, we examined previously (BTSC233, JX6, and SNB19)16,20 and newly (BTSC268 and BTSC475) generated gene expression data obtained upon ZBTB18 expression in GBM cells (Supplementary Fig. 1a, b). Here, ZBTB18 is linked to glioblastoma.