Given the limited number of biopsies available for the analysis, the statistical power of the experiment was low; thus, in order to implement these results, we performed a GlioVis23 in silico analysis to confirm the negative correlation between ZBTB18 and AIF1 (IBA1) (TCGA_GBM dataset: r = −0.43, p Value = 0.00; TCGA_GBM dataset: r = −0,39; p = e-9,68, Fig. 4e and Supplementary Fig. 10d). Here, AIF1 is linked to glioblastoma.