Using transcriptome data from independent HCC cohorts (GSE25097, ICGC-LIRI-JP, and GSE14520), we ascertained that EZH2 was distinctly elevated across all HCC cohorts, accompanied by significant upregulation of the PRC2 complex subunits SUZ12 and EED, of which EZH2 is a constituent (Fig. 1D and Supplementary Fig. 1C). The gene discussed is EZH2; the disease is hepatocellular carcinoma.