Within the T1 cluster, there was a notable enrichment of HNF4 motifs (p = 1 ×10-485), a known tumor suppressor involved in hepatocyte differentiation, along with CEBP (p = 1 × 10−155) and ATF (p = 1 × 10−103) motifs. The gene discussed is HNF4A; the disease is neoplasm.