Of these, 22 (56%) were expressed more highly in neocortical than allocortical regions, including several cell adhesion molecules (DSCAM, PCDH7, PCDH9, LRFN2), teneurins (TENM3) and ephrins (EFNA5), as well as genes with functional links to language acquisition (FOXP2) and neurodevelopmental disorders (MEF2C, AFF2, ZEB2) (Supplementary Data S9). The gene discussed is AFF2; the disease is neurodevelopmental disorder.