CFAP410 and cone-rod dystrophy: This variant is by far the most frequent change detected in CFAP410 patients (see Supplementary Table 3) and it is the only described pathogenic variant localizing in the third leucine-reach repeat domain, although very recently a similar missense variant located closeby but classified as VUS (p.Arg70Gln) has been detected homozygously in one CRD case26.