Notably, a greater level of sorcin expression was detected in PCAND tumor tissues than in PC + T2DM tumor tissues (sorcin IHC scores, PCAND vs. PC + T2DM: 7.10 ± 1.71 (n = 28) vs. 5.85 ± 1.67 (n = 28), P = 0.008; pure PC vs. PCAND: 6.51 ± 1.51 (n = 32) vs. 7.10 ± 1.71 (n = 28), P = 0.136) (Fig. 7a, b). Here, SRI is linked to neoplasm.