Tumor-supporting activity is related to facilitating tumor invasion, proliferation and migration (mediated by CD204, CD206, CXCL16, stabilin-1, and RAGE), M2-like TAM polarization (by CD36, LOX-1, CXCL16, CD163, and RAGE), and tumor angiogenesis (by CD68, Dectin-1, and RAGE). The gene discussed is MRC1; the disease is neoplasm.