CD8A and non-small cell lung carcinoma: Inhibition of glycolysis cooperated with anti-PD-L1 therapy by inducing CD8+ T-cell antitumor effects in mouse NSCLC xenograft models, and elevated levels of overall lysine lactylation (Kla) and specific lactylation of H3K18 (H3K18la) correlated with unfavorable prognosis in NSCLC patients [255].