Immunohistochemistry analysis on the FFPE tissue of 227 CRC-II patients using DFS rate as a measure of survival found a significant prognostic relevance for high expression of CDX2 (p = 0.03) in cases where MUC2 was also expressed, with the absence of SOX2 (p = 0.04) [50]. This evidence concerns the gene CDX2 and colorectal carcinoma.