In contrast, the intestinal type tumors have better survival characteristics and are enriched in TCGAs CIN subgroup [2, 17, 21] Also, CDH1 and TP53 mutations are enriched in the GS and CIN subgroups, respectively, which has prompted the use of these two genes as surrogates [4, 18, 22, 23]. This evidence concerns the gene TP53 and cervical squamous intraepithelial neoplasia.