The results indicated that siRNA-Psmb8 infection markedly prolonged the half-life of the Drp1 protein compared with that in cells infected with siRNA-control (Fig. 7E); however, compared with Ad-GFP infection, Ad-Psmb8 infection reduced the half-life of the Drp1 protein (Fig. 7F). The gene discussed is PSMB8; the disease is infection.