Subsequently, we used SAT snRNA-seq data of two bariatric surgery cohorts from individuals with high BMI to identify 13 unique adipocyte marker genes impacted by the status of the risk allele T of the missense abdominal obesity GWAS variant in trans. One of the 13 trans genes, BCL6, is known to maintain thermogenic fitness in dormant brown adipocytes and oppose white adipocyte cellular identity.78 The gene discussed is BCL6; the disease is Abdominal obesity.