TBX15 and Abdominal obesity: Next, we focused on this common missense abdominal obesity GWAS SNP, rs10494217, in TBX15. The variant is also a known GWAS variant for a related trait, WHR (Figure 2A), and present in two of the three TBX15 transcripts, ENST00000369429 and ENST00000207157 (Figure 2A).