We found that in SAT only adipocytes are enriched for abdominal obesity heritability and show a high level of expression for TBX15. We also identified 13 unique adipocyte marker genes, the adipocyte expression of which is impacted by the risk allele status of the missense variant in trans, consistently across two independent Finnish cohorts, thus exemplifying the gene expression changes induced by rs10494217 and the importance of TBX15 for gene expression in adipocytes. Here, TBX15 is linked to Abdominal obesity.