REN and hypertensive disorder: We obtained multi-organ high-throughput qPCR gene expression data involved in inflammation, renin-angiotensin signaling, sympathetic pathways, metabolism, and fibrosis from adrenal gland, kidney, liver, lung, and spleen in female SHR (n = 3) and age-matched WKY control (n = 3) at time points corresponding to pre-hypertension (8 weeks), hypertension onset (10 and 12 weeks), and chronic hypertension (16 and 24 weeks) (Fig 1).