Analysis of the GSE13898 dataset revealed a notable increase in MET mRNA expression in both Barrett’s esophagus (9.911 ± 0.160) and esophageal adenocarcinoma (9.398 ± 0.171) compared with NSE (8.080 ± 0.073; P < 0.0001; Fig. 1A). Here, ENO2 is linked to esophageal adenocarcinoma.