The c-MET H-scores for NSE and Barrett’s esophagus were 39.10 ± 6.83 and 84.76 ± 10.86 and the c-MET positivity scores were 34.07 ± 5.72 and 55.00 ± 7.87, respectively. The gene discussed is ENO2; the disease is esophageal adenocarcinoma.