BIRC5 and cancer: As we already confirmed co-localization of Survivin with the other CPC proteins (Figure 1E–G), as well as with HP1 and CREST (Figure 2 and Figure S3), particularly after IR, we verified the intracellular patterns for a sub-selection of proteins, including HP1α and INCENP (Figure S6D), CREST and Aurora B (Figure S6E) or PCNA, HP1α and Aurora B (Figure S6F) in normal and cancer cell lines, respectively.