We further explored the DepMap portal to understand the gene effect on NSCLC proliferation and found that the loss of gene function of MYO1E, FAM83A, DKK1, FGA, and TRIB1 showed a negative effect on maximum cell lines of primary and metastatic origin for NSCLC (Figure 9). The gene discussed is DKK1; the disease is non-small cell lung carcinoma.