Our findings indicated that P-selectin is the most effective molecule conjugated to the liposome, facilitating rescue from TAA-induced increases in circulating ALT and thrombocytopenia, compared to other proteins such as E-selectin, L-selectin, galectin-1, CLEC2, and anti-PSGL-1 Ig (Figure 7). The gene discussed is SELPLG; the disease is Thrombocytopenia.