In the mouse model of Mowat–Wilson syndrome, which is caused by a Sip1 gene mutation, Rett syndrome, caused by an inactivation of MeCP2, and Satb2-associated syndrome, which occurs when the expression of transcription factor Satb2 is disrupted, audiogenic stimulation did not cause epileptic seizures. This evidence concerns the gene MECP2 and Rett syndrome.