Mesothelial cells undergo to mesothelial-mesenchymal transition induced by HGF secreted by OC cells, then CAMs promote the expression of pro-tumor factors such as IL-8 and C-X-C motif chemokine ligand 5 (CXCL5) to facilitate dissemination of OC cells (78). The gene discussed is CXCL8; the disease is neoplasm.