CD274 and neoplasm: For instance, positron emission tomography (PET) imaging using 89Zr‐radiolabeled PD‐L1 antibodies has enabled noninvasive quantification of PD‐L1.[3, 9] Similarly, single photon emission computed tomography (SPECT) imaging of 99mTc‐radiolabeled LAG‐3‐targeting nanobodies enables dynamic visualization of LAG‐3 on TILs.[10] Despite these significant advancements, the correlation between tracer tumor uptake and LAG‐3 expression level determined by IHC remains incompletely illustrated.