After observing increased tumor signals of 99mTc‐radiolabeled probes in tumors with elevated expression of LAG‐3 or PD‐L1 (Figure4a,b), we further quantified the correlations among in vivo tumor uptake obtained by region of interest (ROI) analysis, tumor uptake determined through ex vivo γ‐counting, and IHC expression levels. This evidence concerns the gene LAG3 and neoplasm.