With respect to LAG‐3+PD‐L1high immunotyping, it can be observed that LAG‐3+ A549 tumor presented discernible tumor uptake of 99mTc‐HYNIC‐αLAG‐3 at 24 h, and PD‐L1‐high H1975 tumors also displayed a significantly enhanced signal of 125I‐αPD‐L1 at 24 h, with signal peak occurring at 48 h. This evidence concerns the gene CD274 and neoplasm.