As shown in Figure 1H, aripiprazole elicited CRC cell apoptosis in a dose‐dependent manner (0–20 μM), which was further confirmed by the increased expressions of cleaved‐Caspase 3, cleaved‐PARP, Bax, and the decreased expression of Bcl2 upon aripiprazole treatment (Figure 1I). This evidence concerns the gene BCL2 and colorectal carcinoma.