For instance, EVs derived from NK cells carry functional miR-186, which can target genes such as v-Myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (MYCN), Aurora-A kinase (AURKA), transforming growth factor-beta (TGF-β) receptor type 1 (TGFBR1), and transforming growth factor-beta (TGF-β) receptor type 2 (TGFBR2) in neuroblastoma or NK cells. The gene discussed is AURKA; the disease is neuroblastoma.