TP53 and cancer: Based on “c2.cp.kegg.v7.5.1.symbols.gmt” gene set, the enrichment pathways within high-risk PCs encompassed “ECM receptor interaction”, “focal adhesion”, “P53 signaling pathway”, “pathways in cancer”, and “small cell lunger cancer” (Figure 6C); the enrichment pathways within low-risk PCs encompassed “drug metabolism cytochrome P450”, “maturity onset diabetes of the young”, “neuroactive ligand receptor interaction”, and “proximal tubule bicarbonate reclamation” (Figure 6D).