It has also been found to reduce JAK2/STAT3 signaling and induce autophagy through the production of ROS in SKOV3/DDP ovarian tumor cells resistant to cisplatin 29, as well as suppressing the growth of lung cancer by blocking β-catenin induction of the epithelial-mesenchymal transition 31. The gene discussed is JAK2; the disease is ovarian neoplasm.