More specifically, PHGDH, PSAT1, FTCD, SHMT2, MTHFD2L, MTHFD2, MTHFD1L, MTHFD1, GCAT, SARDH, BHMT, CHDH, TYMS, GART, ATIC, ALDH1L2, DHFR, and MTFMT showed elevated expression in tumor tissues. The gene discussed is SHMT2; the disease is neoplasm.