More specifically, PHGDH, PSAT1, FTCD, SHMT2, MTHFD2L, MTHFD2, MTHFD1L, MTHFD1, GCAT, SARDH, BHMT, CHDH, TYMS, GART, ATIC, ALDH1L2, DHFR, and MTFMT showed elevated expression in tumor tissues. The gene discussed is DHFR; the disease is neoplasm.