Our analysis showed that the correlation between the expression of NDC80 complex components and 44 of 109 overlapping genes, including SPAG5, H2AFV, ESPL1, MCM3, TIMELESS, CENPO, DSN1, MIS18A, CKS1B, HMGB2, FBXO5, RFC4, VRK1, SHCBP1, CENPL, POLA2, CHAF1B, UBE2S, MCM6, PCNA, TRAIP, RNASEH2A, CHEK1, GINS1, SNRPD1, MCM2, RFC2, ZWINT, KPNA2, FAM72B, CKS2, CDC7, CCNB1, KIF23, C17orf53, FANCD2, DNAJC9, FAM72D, CDK1, LRR1, CCNF, RAD54L, CENPH, and RACGAP1, was significantly higher in the tumor context compared to the normal tissues (Figure 6F). The gene discussed is SPAG5; the disease is neoplasm.