For instance, NDC80 is reported to be upregulated and predict poor prognosis in several human cancers, including lung adenocarcinoma (LUAD)3, pancreatic adenocarcinoma (PAAD)4, colon adenocarcinoma (COAD)5, osteosarcoma6, liver hepatocellular carcinoma (LIHC)7, and gastric cancer8. This evidence concerns the gene NDC80 and cancer.